Medical Guidelines

For your safety, it is essential to stop using any medication that is not vital for life support before participating in an Ayahuasca ceremony. This includes pharmaceuticals that work to suppress symptoms, as many can interfere with the Ayahuasca experience. Ideally, medications should be discontinued at least six weeks before, and up to three weeks after, the ceremony to ensure they do not reduce the healing potential or alter the effects of Ayahuasca.

It’s important to trust that Ayahuasca has the potential to cleanse and heal the body, including ailments that may have required medication. Certain medications, however, can be dangerous when combined with Ayahuasca, as it acts as an MAOI (Monoamine Oxidase Inhibitor). This means it can interact with specific types of medication. Please consult with the ceremony personnel and your healthcare provider about any medications you are taking to avoid harmful interactions.

For example, it’s crucial to taper off antidepressants (SSRIs, SNRIs, TCAs, SARIs), mood stabilizers, and other psycho-pharmaceuticals well in advance of the ceremony to ensure no traces remain in your system.

Do not abruptly stop any medication without medical supervision.

Important Notes:

• You are fully responsible for informing the retreat organizers about any past or current drug use, serious physical or psychological conditions, or prescription medications you are currently taking.

• If you are under psychiatric treatment, taking psycho-pharmaceuticals, or have a history of substance use (such as heroin, cocaine, amphetamines), you must consult with Inekawa at least one month before the Ayahuasca retreat.

• The use of other teacher plants or psychoactive substances (such as mushrooms, marijuana, DMT, LSD) is not encouraged. If you have any questions regarding substances, please contact us.

• If you are taking medications or supplements that are necessary before the ceremony, it is important to discuss these with our medical team beforehand.

• For individuals with health concerns such as untreated tuberculosis, heart or liver conditions, or pregnancy, please contact us to determine if Ayahuasca is suitable for you.

Psychological Safety: 

Individuals with mental health conditions, such as bipolar disorder, schizophrenia, or personality disorders, are at a higher risk when using Ayahuasca. If you have a history of these or other mental disorders, it is essential to inform Inekawa and consult with a healthcare provider.

All potential guests will be asked to complete a screening questionnaire to assess the presence of any risk factors. We prioritize the safety of our participants and ensure that experienced staff and facilitators are present throughout the ceremony to address any issues in a controlled, caring, and professional manner. Our commitment to your well-being includes 24-hour supervision, creating a safe environment to work with Ayahuasca.

Medication and Drug Interactions with Ayahuasca (MAOI): 

Ayahuasca, being an MAOI, can cause dangerous interactions with certain pharmaceutical and recreational drugs. Some medications and substances can lead to life-threatening conditions, such as serotonin syndrome, when combined with Ayahuasca. These include, but are not limited to:

• Antidepressants: SSRIs, SNRIs, TCAs, SARIs

• Antihypertensive/High Blood Pressure Medications

• Appetite Suppressants/Diet Pills

• Medications for Breathing Problems: Asthma, bronchitis treatments

• Antihistamines: Including medications for colds, sinus issues, hay fever, or allergies containing dextromethorphan (DXM)

• CNS Depressants: Xanax, Ativan

• Vasodilators

• Antipsychotics

• Barbiturates

Plants and Illegal or Recreational Drugs to Avoid: Combining Ayahuasca with certain plants and illegal or recreational drugs is extremely dangerous and can be fatal. Avoid the following substances:

• Cocaine, amphetamines, ephedrine

• MDMA (Ecstasy), MDA, MDEA, PMA

• Opiates (heroin, morphine, codeine)

• Dextromethorphan (DXM)

• Mescaline, Phenethylamines

• 5-MEO-DMT

• Alcohol

• Kratom

• Kava

• Nutmeg

For a detailed list of medications and substances contraindicated with Ayahuasca, please refer to our Safety Guidelines. If you have any questions about medications, consult your healthcare provider and contact us for clarification.

At Inekawa, we are committed to the psychological and physical safety of each participant. While Ayahuasca has the potential to offer profound healing, it must be approached with proper care, preparation, and understanding of potential risks. By following the above precautions, you can safely engage in this transformative journey.

For any medical inquiries, please feel free to contact us at medical@inekawa.org.